Functional IL‐10 Gene Polymorphism Is Associated with Chagas Disease Cardiomyopathy

Functional IL-10 gene polymorphism is associated with Chagas disease cardiomyopathy.

This study was designed to determine whether the functional IL-10 gene polymorphism -1082G/A is associated with the development of cardiomyopathy in individuals infected with Trypanosoma cruzi and whether interleukin (IL)-10 expression can be correlated with patients' cardiac function. Our results demonstrated that the polymorphic allele, which correlates with lower expression of IL-10, was ass...

IL10 gene polymorphism is associated with preschool atopy and early-life asthma after bronchiolitis in infancy

Korppi (MK), Nuolivirta (KN), Lauhkonen (EL), Holster (AH), Teräsjärvi (JT), Vuononvirta (JV), Helminen (MH), He (QH), Koponen (PK) IL10 gene polymorphism is associated with preschool atopy and early-life asthma after bronchiolitis in infancy background: Variations in genes regulating innate immunity responses may be associated with susceptibility to asthma or atopy after early-life bronchiolit...

Common Genetic Variant of insig2 Gene rs7566605 Polymorphism Is Associated with Severe Obesity in North India

Background: Obesity is a very common disorder resulting from an imbalance between food intake and energy expenditure, and it has a substantial impact on the development of chronic diseases.  The aim of this study was to examine the association of INSIG2 (rs7566605) gene polymorphism with obesity and obesity associated phenotypes in North Indian subjects. Methods: The variants were investig...

Zinc Finger 259 Gene Polymorphism rs964184 is Associated with Serum Triglyceride Levels and Metabolic Syndrome

Metabolic syndrome (MetS) is characterized by a cluster of cardiovascular risk factors that include: abdominal obesity, dyslipidaemia, hypertension, insulin resistance and impaired glucose tolerance. Recent genome wide association studies have identified several susceptibility regions involved in lipid metabolism that are also associated with MetS. We have explored the association of 9 genetic ...

The 763C>G Polymorphism of The Secretory PLA2IIa Gene Is Associated with Endometriosis in Iranian Women